Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 10/20 | 0.38 |
| ▸ | RARG | P13631 | 9/20 | 0.38 |
| ▸ | RARA | P10276 | 8/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.38 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 7/20 | 0.38 |
| ▸ | RXRB | P28702 | 5/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30041233 | 1.00 | CA12 (0.38) | CA12CA1CA2CA4CA9 | |
| SCHEMBL23704795 | 1.00 | CA12 (0.38) | CA12CA1CA2CA4CA9 | |
| SCHEMBL31396317 | 1.00 | CA12 (0.38) | CA12CA1CA2CA4CA9 | |
| SCHEMBL23706097 | 1.00 | CA12 (0.38) | CA12CA1CA2CA4CA9 | |
| SCHEMBL31396120 | 1.00 | CA12 (0.38) | CA12CA1CA2CA4CA9 | |
| SCHEMBL23705080 | 1.00 | CA12 (0.38) | CA12CA1CA2CA4CA9 | |
| SCHEMBL23714588 | 0.89 | NPC1 (0.41) | CA1CA2RARBRARGRARA | |
| SCHEMBL30041183 | 0.88 | KDM1A (0.38) | ALDH1A1KDM1A | |
| SCHEMBL23714754 | 0.86 | RARA (0.31) | RARBRARGRARARXRARXRB | |
| SCHEMBL23714701 | 0.86 | CA12 (0.38) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739684-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | Janssen Pharmaceutica NV (BE) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008060-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-09 | — | — | WO | disclosed |
| CN-115297861-A | Compound and use thereof | 福宏治疗公司 | 2022-11-04 | — | — | CN | disclosed |