Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | DRD3 | P35462 | 6/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.31 |
| ▸ | DRD4 | P21917 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25186921 | 0.84 | DRD2 (0.38) | DRD2DRD3HTR1DSTSCA1 | |
| SCHEMBL1129301 | 0.70 | DRD2 (0.34) | DRD2DRD3HTR1DSTSCHRM1 | |
| SCHEMBL10158670 | 0.70 | STS (0.42) | DRD2DRD3HTR1DSTSCA1 | |
| SCHEMBL5026108 | 0.70 | STS (0.64) | DRD2DRD3HTR1DSTSCA1 | |
| SCHEMBL4427945 | 0.70 | STS (0.59) | DRD2DRD3HTR1DSTSCA1 | |
| SCHEMBL21468547 | 0.69 | STS (0.62) | DRD2DRD3HTR1DSTSCA1 | |
| SCHEMBL19460607 | 0.69 | STS (0.40) | DRD2DRD3HTR1DSTSCA1 | |
| SCHEMBL30935381 | 0.68 | STS (0.39) | DRD2DRD3HTR1DSTSCA1 | |
| SCHEMBL30831471 | 0.68 | DRD2 (0.42) | DRD2DRD3HTR1DHSD11B1 | |
| SCHEMBL1933990 | 0.67 | DRD2 (0.41) | DRD2DRD3HTR1DSTSCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |