Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158670 | 0.82 | STS (0.42) | STSDRD2DRD3HTR1DCA1 | |
| SCHEMBL5026108 | 0.77 | STS (0.64) | STSDRD2DRD3HTR1DCA1 | |
| SCHEMBL4427945 | 0.77 | STS (0.59) | STSDRD2DRD3HTR1DCA1 | |
| SCHEMBL21468547 | 0.75 | STS (0.62) | STSDRD2DRD3HTR1DCA1 | |
| SCHEMBL6557372 | 0.75 | PTGS1 (0.42) | STSDRD2DRD3HTR1DCA1 | |
| SCHEMBL8438305 | 0.73 | RXRA (0.40) | STSDRD2DRD3HTR1DCA1 | |
| SCHEMBL14053247 | 0.71 | BACE1 (0.38) | KDM1A | |
| SCHEMBL3464939 | 0.70 | DRD2 (0.35) | DRD2DRD3HTR1DCA1CA2 | |
| SCHEMBL25186921 | 0.70 | DRD2 (0.38) | STSDRD2DRD3HTR1DCA1 | |
| SCHEMBL1513290 | 0.70 | MAOA (0.53) | STSDRD2DRD3HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |