Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSPA9 | P38646 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23714634 | 0.83 | RARB (0.36) | RARBRARGRARAGAAHSPA9 | |
| SCHEMBL1396642 | 0.79 | RARB (0.49) | RARBRARGRARABRD4CMA1 | |
| SCHEMBL23714713 | 0.77 | RARB (0.55) | RARBRARGRARAHSPA9 | |
| SCHEMBL23714715 | 0.77 | RARB (0.55) | RARBRARGRARAHSPA9 | |
| SCHEMBL30058891 | 0.74 | KDM1A (0.46) | CMA1AHRAPPBACE1 | |
| SCHEMBL23704864 | 0.74 | KDM1A (0.46) | CMA1AHRAPPBACE1 | |
| SCHEMBL23715375 | 0.71 | BACE1 (0.33) | RARBRARGRARABRD4CMA1 | |
| SCHEMBL23706042 | 0.70 | BACE1 (0.40) | RARBRARGRARALMNAAKR1B1 | |
| SCHEMBL6224511 | 0.69 | RARB (0.49) | RARBRARGRARACMA1AHR | |
| SCHEMBL30885033 | 0.69 | RARB (0.49) | RARBRARGRARACMA1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |