Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1396642 | 0.77 | RARB (0.49) | BRD4CMA1AHRGAAL3MBTL1 | |
| SCHEMBL24275639 | 0.73 | BACE1 (0.49) | BACE1BACE2CTSDAPP | |
| SCHEMBL6278100 | 0.73 | PGR (0.37) | BRD4CMA1AHRGAAL3MBTL1 | |
| SCHEMBL23714890 | 0.71 | RARB (0.36) | BACE1BRD4CMA1AHRGAA | |
| SCHEMBL26145043 | 0.71 | GAA (0.34) | BACE1BRD4CMA1AHRGAA | |
| SCHEMBL2343653 | 0.69 | GAA (0.39) | BRD4CMA1AHRGAAL3MBTL1 | |
| SCHEMBL23704986 | 0.69 | BACE1 (0.41) | BACE1LMNAAKR1B1 | |
| Hydrochloric Acid SCHEMBL6518062 | 0.68 | GAA (0.38) | BRD4CMA1AHRGAAL3MBTL1 | |
| SCHEMBL23715372 | 0.68 | BACE1 (0.35) | BACE1CMA1AHRBACE2CTSD | |
| SCHEMBL21255481 | 0.67 | CMA1 (0.36) | BACE1BRD4CMA1AHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |