Sugi Predict

Sugi Predict / Compounds / SCHEMBL2371500

SCHEMBL2371500

SCHEMBL2371500

O=C(NC(=O)c1ccccc1Cl)Nc1ccc(OCCc2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.61
▸ GCGR P47871 1/20 0.54
▸ PYGL P06737 1/20 0.53
▸ RAB9A P51151 4/20 0.52
▸ NPC1 O15118 3/20 0.52
▸ PPARA Q07869 4/20 0.51
▸ ALDH1A1 P00352 1/20 0.50
▸ SMO Q99835 2/20 0.49
▸ LTA4H P09960 1/20 0.49
▸ POLB P06746 2/20 0.48
▸ PKM P14618 1/20 0.48
▸ PCTP Q9UKL6 1/20 0.47
▸ FFAR1 O14842 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11240828 0.94 TDP1 (0.60) TDP1GCGRPYGLRAB9ANPC1
SCHEMBL7832960 0.89 TDP1 (0.63) TDP1GCGRPYGLRAB9ANPC1
SCHEMBL11250867 0.88 TDP1 (0.63) TDP1GCGRPYGLRAB9ANPC1
SCHEMBL11383399 0.85 TDP1 (0.54) TDP1GCGRPYGLRAB9ANPC1
SCHEMBL11385899 0.83 TDP1 (0.60) TDP1GCGRPYGLRAB9ANPC1
SCHEMBL13036785 0.83 TDP1 (0.70) TDP1GCGRPYGLRAB9ANPC1
SCHEMBL11242279 0.82 TDP1 (0.61) TDP1GCGRPYGLRAB9ANPC1
SCHEMBL11243370 0.81 GCGR (0.62) TDP1GCGRPYGLRAB9ANPC1
SCHEMBL11385942 0.81 GCGR (0.62) TDP1GCGRPYGLRAB9ANPC1
SCHEMBL11138391 0.81 TDP1 (0.70) TDP1GCGRPYGLRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845944-A1 ACTIVE SUBSTANCE COMBINATIONS COMPRISING PYRETHROIDS AND INSECT-DEVELOPMENT INHIBITORS BAYER AG (DE) 1998-06-10 — — EP claimed
WO-1997006687-A1 ACTIVE SUBSTANCE COMBINATIONS COMPRISING PYRETHROIDS AND INSECT-DEVELOPMENT INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-27 — — WO claimed
CN-113382996-B Theophylline derivatives with nematicidal activity, agronomic compositions and related uses 高文作物保护公司 2024-07-16 — — CN disclosed
EP-3962900-A1 ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF ISAGRO S.p.A. (IT) 2022-03-09 — — EP disclosed
CN-113784952-A Esters of non-aromatic heterocyclic compounds with nematicidal activity, their agronomic compositions and uses thereof 伊萨格罗股份公司 2021-12-10 — — CN disclosed
CN-108471752-B Heterocyclic trifluoroalkenyl compounds having nematicidal activity, agronomic compositions thereof and uses thereof 伊萨格罗股份公司 2021-11-09 — — CN disclosed
CN-113382996-A Theophylline derivatives with nematicidal activity, agronomic compositions thereof and related uses 伊萨格罗股份公司 2021-09-10 — — CN disclosed
WO-2020222118-A1 ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF. ISAGRO S.P.A. (IT) 2020-11-05 — — WO disclosed
EP-3436433-A1 DERIVATIVES OF PYRROLE-2,5-DIONES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMICAL COMPOSITIONS AND USE THEREOF. ISAGRO S.p.A. (IT) 2019-02-06 — — EP disclosed
EP-3393248-A1 USE OF CRYSTALLINE FORMS OF COPPER SALICYLATE FOR THE CONTROL OF PHYTOPATHOGENIC BACTERIA ISAGRO S.p.A. (IT) 2018-10-31 — — EP disclosed
US-20180271097-A1 HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF ISAGRO S.P.A. (IT) 2018-09-27 — — US disclosed
WO-2000020415-A1 PHENYLACETIC ACID HETEROCYCLYL AMIDES HAVING AN INSECTICIDAL EFFECT BAYER AKTIENGESELLSCHAFT (DE) 2000-04-13 — — WO disclosed
WO-2000018742-A1 SULFONYLTRIAZOL DERIVATIVES AND THEIR USE FOR COMBATING MICRO-ORGANISMS BAYER AKTIENGESELLSCHAFT (DE) 2000-04-06 — — WO disclosed
WO-2000015620-A1 SULFONYL OXAZOLONES AND THEIR USE FOR COMBATING UNDESIRABLE MICROORGANISMS BAYER AKTIENGESELLSCHAFT (DE) 2000-03-23 — — WO disclosed
WO-2000010970-A1 METHOXIMINOPHENYLACETIC ACID AMIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-03-02 — — WO disclosed
WO-2000003995-A1 DIPHENYLIMIDAZOLINES BAYER AKTIENGESELLSCHAFT (DE) 2000-01-27 — — WO disclosed
WO-1999043649-A1 ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS BAYER AKTIENGESELLSCHAFT (DE) 1999-09-02 — — WO disclosed
WO-1999016748-A1 UTILIZING SPIROCYCLIC PHENYL KETO-ENOLS AS PESTICIDES AND HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-04-08 — — WO disclosed
EP-0845944-A1 ACTIVE SUBSTANCE COMBINATIONS COMPRISING PYRETHROIDS AND INSECT-DEVELOPMENT INHIBITORS BAYER AG (DE) 1998-06-10 — — EP disclosed
WO-1997006687-A1 ACTIVE SUBSTANCE COMBINATIONS COMPRISING PYRETHROIDS AND INSECT-DEVELOPMENT INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180271097-A1 HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF CYP8B1, CYCS, LSS TDP1 4272/4885GCGR 4691/4885PYGL 4623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.