Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.56 |
| ▸ | GCGR | P47871 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385899 | 0.95 | TDP1 (0.60) | TDP1NPC1RAB9ASMN1; SMN2NOX1 | |
| SCHEMBL11243370 | 0.93 | GCGR (0.62) | TDP1NPC1RAB9ASMN1; SMN2NOX1 | |
| SCHEMBL11385942 | 0.93 | GCGR (0.62) | TDP1NPC1RAB9ASMN1; SMN2NOX1 | |
| SCHEMBL11235155 | 0.91 | RAB9A (0.63) | TDP1NPC1RAB9ASMN1; SMN2NOX1 | |
| SCHEMBL11242279 | 0.91 | TDP1 (0.61) | TDP1NPC1RAB9ASMN1; SMN2NOX1 | |
| SCHEMBL11236585 | 0.91 | TDP1 (0.58) | TDP1NPC1RAB9ASMN1; SMN2NOX1 | |
| SCHEMBL11228921 | 0.89 | TDP1 (0.56) | TDP1NPC1RAB9ASMN1; SMN2GCGR | |
| SCHEMBL2371500 | 0.88 | TDP1 (0.61) | TDP1NPC1RAB9AGCGRLTA4H | |
| SCHEMBL4627493 | 0.88 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LTA4HMEN1 | |
| SCHEMBL11248869 | 0.88 | TDP1 (0.64) | TDP1NPC1RAB9ASMN1; SMN2GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |