Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31543348 | 0.71 | GRM5 (0.44) | GRM5ALDH1A1HPGDCTH | |
| SCHEMBL531659 | 0.71 | GRM5 (0.44) | GRM5ALDH1A1HPGDCTH | |
| SCHEMBL3507575 | 0.70 | GRM5 (0.42) | GRM5ALDH1A1HPGDCTH | |
| SCHEMBL3507580 | 0.70 | GRM5 (0.42) | GRM5ALDH1A1HPGDCTH | |
| SCHEMBL3507578 | 0.70 | GRM5 (0.42) | GRM5ALDH1A1HPGDCTH | |
| SCHEMBL18105408 | 0.69 | KMT2A (0.35) | ALDH1A1 | |
| SCHEMBL13896497 | 0.67 | ALDH1A1 (0.43) | GRM5ALDH1A1HPGDCTH | |
| SCHEMBL21535110 | 0.67 | GRM5 (0.38) | GRM5ALDH1A1HPGDCTH | |
| SCHEMBL12448235 | 0.66 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL2769666 | 0.65 | KDM4E (0.50) | GRM5ALDH1A1HPGDCTH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |