Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25107060 | 0.85 | MEN1 (0.35) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18792399 | 0.80 | ATM (0.37) | KMT2AMEN1CES2CES1MAPT | |
| SCHEMBL17726017 | 0.79 | KMT2A (0.36) | KMT2AMEN1EGFRG6PC1CES2 | |
| SCHEMBL19085533 | 0.76 | AKT1 (0.36) | ATMAKT1 | |
| SCHEMBL25113036 | 0.74 | AKT1 (0.37) | KMT2AMEN1EGFRCES2CES1 | |
| SCHEMBL12448235 | 0.74 | ALDH1A1 (0.41) | KMT2AMEN1CES2CES1MAPT | |
| SCHEMBL26482446 | 0.72 | TSHR (0.32) | KMT2AMEN1CES1MAPTLMNA | |
| SCHEMBL23715031 | 0.69 | GRM5 (0.34) | ALDH1A1 | |
| SCHEMBL21444356 | 0.68 | AKT1 (0.36) | ATMAKT1 | |
| SCHEMBL29720126 | 0.68 | MEN1 (0.36) | KMT2AMEN1EGFRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447464-B2 | Compounds with spirobifluorene-structures | MERCK PATENT GMBH (DE) | 2022-09-20 | — | — | US | disclosed |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | MERCK PATENT GMBH (DE) | 2022-05-10 | — | — | US | disclosed |
| US-20210363159-A1 | HETEROCYCLIC COMPOUND FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-11-25 | — | — | US | disclosed |
| US-10636979-B2 | Heterocyclic compounds with dibenzazapine structures | MERCK PATENT GMBH (DE) | 2020-04-28 | — | — | US | disclosed |
| US-20200098996-A1 | MIXTURES COMPRISING AT LEAST TWO ORGANOFUNCTIONAL COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-03-26 | — | — | US | disclosed |
| US-20200031827-A1 | COMPOUNDS HAVING VALEROLACTAM STRUCTURES | MERCK PATENT GMBH (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| US-20190194164-A1 | COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES | MERCK PATENT GMBH (DE) | 2019-06-27 | — | — | US | disclosed |
| US-20160285009-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447464-B2 | Compounds with spirobifluorene-structures | SLCO1B3, SLCO4C1, SLCO1B1 | KMT2A 3037/4885MEN1 1205/4885EGFR 1580/4885 |
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | NQO1, DDT, ETV6 | KMT2A 757/4885MEN1 1480/4885EGFR 1438/4885 |
| US-10636979-B2 | Heterocyclic compounds with dibenzazapine structures | DDT, MAOA, MAOB | KMT2A 678/4885MEN1 4457/4885EGFR 2169/4885 |
| US-20200031827-A1 | COMPOUNDS HAVING VALEROLACTAM STRUCTURES | ACE, CYP3A4, CYP2D6 | KMT2A 1161/4885MEN1 2045/4885EGFR 139/4885 |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | NQO1, DDT, ETV6 | KMT2A 757/4885MEN1 1480/4885EGFR 1438/4885 |
| US-20190194164-A1 | COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES | SLCO1B3, SLCO4C1, SLCO1B1 | KMT2A 3037/4885MEN1 1205/4885EGFR 1580/4885 |
| US-20210363159-A1 | HETEROCYCLIC COMPOUND FOR USE IN ELECTRONIC DEVICES | DDT, NQO1, CYP2E1 | KMT2A 722/4885MEN1 1174/4885EGFR 2077/4885 |
| US-20160285009-A1 | Organic Electroluminescent Materials and Devices | OCIAD1, OCIAD2, JUND | KMT2A 3021/4885MEN1 4134/4885EGFR 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.