⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705070 | 0.82 | NR3C1 (0.30) | — | |
| SCHEMBL25497844 | 0.78 | NR3C1 (0.33) | — | |
| SCHEMBL23704798 | 0.76 | NR3C1 (0.32) | — | |
| SCHEMBL23704874 | 0.72 | NR3C1 (0.31) | — | |
| SCHEMBL23715054 | 0.67 | — | — | |
| SCHEMBL23714873 | 0.64 | MAPK1 (0.30) | — | |
| SCHEMBL28988481 | 0.60 | PRKCG (0.32) | — | |
| SCHEMBL10440200 | 0.60 | NR3C1 (0.35) | — | |
| SCHEMBL32691431 | 0.60 | BACE1 (0.31) | — | |
| SCHEMBL23714685 | 0.60 | CHRNA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |