Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75205 | 0.79 | PPID (0.69) | SMN1; SMN2PPIDMAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL3926946 | 0.78 | PPID (0.68) | SMN1; SMN2PPIDMAPTALDH1A1HTT | |
| SCHEMBL2073087 | 0.76 | MEN1 (0.52) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28079753 | 0.76 | ALDH1A1 (0.44) | SMN1; SMN2PPIDMEN1KMT2AMAPT | |
| SCHEMBL7202692 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2PPIDTDP1MEN1KMT2A | |
| Ethyl Acetate SCHEMBL27687931 | 0.74 | SMN1; SMN2 (0.69) | SMN1; SMN2PPIDTDP1MEN1KMT2A | |
| Acrylic Acid Ethyl Ester SCHEMBL7200790 | 0.72 | SMN1; SMN2 (0.61) | SMN1; SMN2PPIDTDP1MEN1KMT2A | |
| SCHEMBL12559711 | 0.72 | PPID (0.64) | SMN1; SMN2PPIDTDP1MEN1KMT2A | |
| SCHEMBL19273403 | 0.72 | MEN1 (0.52) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6322176 | 0.72 | MEN1 (0.52) | SMN1; SMN2TDP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |