Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | IL1B | P01584 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26639952 | 0.85 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL26620234 | 0.84 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL20265238 | 0.77 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL3314902 | 0.74 | MEN1 (1.00) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL30645379 | 0.74 | MEN1 (1.00) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL29728200 | 0.74 | MEN1 (1.00) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL8856100 | 0.74 | MEN1 (0.66) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL4501549 | 0.74 | P2RX7 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL20194455 | 0.73 | KCNJ11 (0.59) | ALDH1A1KMT2AMEN1GAAPKM | |
| SCHEMBL30640474 | 0.73 | KCNJ11 (0.59) | ALDH1A1KMT2AMEN1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021152149-A1 | RAS INHIBITORS AND METHODS OF USING THE SAME | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2021-08-05 | — | — | WO | disclosed |