Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23715988 | 0.85 | IDO1 (0.40) | IDO1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL23716096 | 0.84 | IDO1 (0.37) | IDO1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL23716379 | 0.82 | IDO1 (0.38) | IDO1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL23716186 | 0.77 | IDO1 (0.41) | IDO1TAAR1KMT2ALMNA | |
| SCHEMBL23715875 | 0.74 | IDO1 (0.37) | IDO1L3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL23715909 | 0.73 | ANO1 (0.34) | MAPTTAAR1 | |
| SCHEMBL23716362 | 0.69 | IDO1 (0.39) | IDO1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL23716034 | 0.68 | IDO1 (0.38) | IDO1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL658518 | 0.68 | CA2 (0.67) | L3MBTL1NPC1RAB9ACTBP2MAPK8 | |
| SCHEMBL4226247 | 0.67 | IDO1 (0.48) | IDO1L3MBTL1NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |