SCHEMBL2371618

SCHEMBL2371618

[CH2]NS(=O)(=O)c1ccccc1Br

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
MAPT P10636 1/20 0.53
PLCG1 P19174 1/20 0.52
RECQL P46063 2/20 0.49
POLB P06746 3/20 0.47
EDNRA P25101 2/20 0.45
EDNRB P24530 1/20 0.45
TDP1 Q9NUW8 1/20 0.40
FBP1 P09467 1/20 0.39
MCL1 Q07820 1/20 0.39
AKR1B1 P15121 1/20 0.39
BRD4 O60885 1/20 0.38
KLK7 P49862 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2371242 0.80 FABP4 (0.43) CA1CA2CA4CA6MAPT
SCHEMBL6743749 0.80 CA1 (0.58) CA1CA2CA4CA6MAPT
SCHEMBL6234991 0.78 CA1 (0.61) CA1CA2CA4CA6MAPT
SCHEMBL1291097 0.78 CA1 (0.56) CA1CA2CA4CA6MAPT
SCHEMBL1767645 0.78 CA1 (0.56) CA1CA2CA4CA6MAPT
SCHEMBL30784566 0.78 CA1 (0.56) CA1CA2CA4CA6MAPT
SCHEMBL2372874 0.76 RXFP1 (0.54) CA1CA2CA4CA6EDNRA
SCHEMBL264098 0.75 CA1 (0.52) CA1CA2CA4CA6MAPT
SCHEMBL15915609 0.75 EDNRA (0.54) CA1CA2CA4CA6MAPT
SCHEMBL30565211 0.75 CA1 (0.52) CA1CA2CA4CA6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP claimed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US claimed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO claimed
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP disclosed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS STS, ARSA, TST CA1 4599/4885CA2 3102/4885CA4 3878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.