Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716188 | 0.82 | ANO1 (0.33) | MAPTMAPK1 | |
| SCHEMBL23716075 | 0.74 | IDO1 (0.40) | LMNA | |
| SCHEMBL23715875 | 0.73 | IDO1 (0.37) | LMNA | |
| SCHEMBL23716232 | 0.72 | IDO1 (0.36) | LMNAHTT | |
| SCHEMBL23716108 | 0.70 | ANO1 (0.34) | MAPTMAPK1 | |
| SCHEMBL23716341 | 0.69 | ANO1 (0.33) | MAPTMAPK1 | |
| SCHEMBL10240551 | 0.68 | TRPA1 (0.43) | BACE1KDM4CKDM4ELMNATP53 | |
| SCHEMBL13226798 | 0.67 | CYP4F2 (0.37) | BACE1KDM4CKDM4ELMNATP53 | |
| SCHEMBL1695325 | 0.67 | CSNK2A1 (0.45) | BACE1KDM4C | |
| SCHEMBL14491132 | 0.67 | CYP4F2 (0.47) | BACE1KDM4CKDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |