Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 5/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25315406 | 0.83 | ALDH1A1 (0.72) | ALDH1A1HPGDXDH | |
| SCHEMBL17663881 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDS1PR1S1PR3XDH | |
| SCHEMBL3082468 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDS1PR1S1PR3LRRK2 | |
| SCHEMBL29921040 | 0.79 | BCL9 (0.48) | — | |
| SCHEMBL23834723 | 0.79 | BCL9 (0.48) | — | |
| SCHEMBL18033389 | 0.79 | SMPD1 (0.53) | — | |
| SCHEMBL2564871 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HPGD | |
| SCHEMBL25315154 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HPGDXDH | |
| SCHEMBL20787410 | 0.76 | LRRK2 (0.56) | ALDH1A1HPGDS1PR1S1PR3LRRK2 | |
| SCHEMBL17708372 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HPGDS1PR1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |