Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716362 | 0.82 | IDO1 (0.39) | ALDH1A1TDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL23716034 | 0.80 | IDO1 (0.38) | ALDH1A1TDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL23716096 | 0.79 | IDO1 (0.37) | ALDH1A1TDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL23716382 | 0.72 | LOXL2 (0.42) | KMT2ASMN1; SMN2TSHRL3MBTL1IDO1 | |
| SCHEMBL27760048 | 0.69 | IDO1 (0.47) | ALDH1A1L3MBTL1IDO1NPC1RAB9A | |
| SCHEMBL23716379 | 0.67 | IDO1 (0.38) | ALDH1A1KMT2ATDP1MAPTSMN1; SMN2 | |
| SCHEMBL23715988 | 0.66 | IDO1 (0.40) | MAPTLMNAL3MBTL1IDO1NPC1 | |
| SCHEMBL11761824 | 0.65 | GABRA1 (0.58) | GABRA1GABRG2GABRB3KDM4EALDH1A1 | |
| SCHEMBL10445460 | 0.65 | NPC1 (0.47) | ALDH1A1KMT2ATDP1MAPTSMN1; SMN2 | |
| SCHEMBL11761830 | 0.65 | GABRA1 (0.58) | GABRA1GABRG2GABRB3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |