Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.43 |
| ▸ | PNMT | P11086 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23715951 | 0.87 | GRM2 (0.34) | IDO1PNMTTAAR1PIK3CA | |
| SCHEMBL23716186 | 0.78 | IDO1 (0.41) | IDO1PNMTTAAR1POLBHSP90AA1 | |
| SCHEMBL23715780 | 0.74 | IDO1 (0.42) | IDO1PNMTTAAR1LMNAGAA | |
| SCHEMBL23716007 | 0.74 | IDO1 (0.42) | IDO1TAAR1 | |
| SCHEMBL23716075 | 0.74 | IDO1 (0.40) | IDO1PNMTTAAR1POLBHSP90AA1 | |
| SCHEMBL23715862 | 0.73 | IDO1 (0.41) | IDO1PNMTTAAR1LMNAGAA | |
| SCHEMBL23716370 | 0.72 | IDO1 (0.44) | IDO1PNMTTAAR1LMNAGAA | |
| SCHEMBL23716176 | 0.71 | IDO1 (0.40) | IDO1PNMTTAAR1LMNAGAA | |
| Hydrochloric Acid SCHEMBL213651 | 0.71 | IDO1 (0.61) | IDO1PNMTTAAR1POLBHSP90AA1 | |
| SCHEMBL1029174 | 0.69 | SLC6A4 (0.54) | IDO1PNMTTAAR1POLBHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |