Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716262 | 0.87 | IDO1 (0.43) | IDO1PNMTTAAR1PIK3CA | |
| SCHEMBL23715909 | 0.80 | ANO1 (0.34) | GRM2ANO1MAPTMAPK1PNMT | |
| SCHEMBL23716007 | 0.77 | IDO1 (0.42) | IDO1TAAR1 | |
| SCHEMBL23716188 | 0.76 | ANO1 (0.33) | GRM2ANO1MAPTMAPK1KCNK3 | |
| SCHEMBL23716287 | 0.75 | ANO1 (0.34) | GRM2ANO1MAPTMAPK1TRPV1 | |
| SCHEMBL23716108 | 0.72 | ANO1 (0.34) | GRM2ANO1MAPTMAPK1KCNK3 | |
| SCHEMBL3397980 | 0.72 | CA2 (0.47) | GRM2ANO1MAPTMAPK1PIK3CA | |
| SCHEMBL23716099 | 0.71 | ANO1 (0.34) | GRM2ANO1MAPTMAPK1PNMT | |
| SCHEMBL23715911 | 0.71 | CCR3 (0.37) | ANO1MAPTMAPK1PTGER4 | |
| SCHEMBL23716341 | 0.70 | ANO1 (0.33) | GRM2ANO1MAPTMAPK1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |