Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4320859 | 0.78 | HCAR2 (0.49) | IDO1AGXTTAAR1MAPK8MAOB | |
| SCHEMBL4320854 | 0.78 | HCAR2 (0.49) | IDO1AGXTTAAR1MAPK8MAOB | |
| SCHEMBL23715951 | 0.77 | GRM2 (0.34) | IDO1TAAR1 | |
| SCHEMBL21394861 | 0.74 | TAAR1 (0.46) | IDO1AGXTTAAR1MAPK8MAOB | |
| SCHEMBL23716262 | 0.74 | IDO1 (0.43) | IDO1TAAR1 | |
| SCHEMBL27791783 | 0.73 | TAAR1 (0.52) | IDO1AGXTTAAR1MAPK8MAOB | |
| Hydrochloric Acid SCHEMBL214750 | 0.72 | HTR3E (0.59) | IDO1AGXTTAAR1MAPK8MAOB | |
| SCHEMBL19597972 | 0.70 | HCAR2 (0.44) | IDO1AGXTTAAR1MAPK8MAOB | |
| SCHEMBL29846287 | 0.70 | TAAR1 (0.52) | IDO1AGXTTAAR1MAPK8MAOB | |
| SCHEMBL1623365 | 0.70 | HTR3E (0.61) | IDO1AGXTTAAR1MAPK8MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |