Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 18/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 12/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716350 | 0.82 | S1PR3 (0.55) | S1PR3S1PR4S1PR2S1PR1GBA1 | |
| SCHEMBL23716432 | 0.81 | S1PR3 (0.52) | S1PR3S1PR4S1PR2S1PR1 | |
| SCHEMBL23716027 | 0.77 | S1PR3 (0.56) | S1PR3S1PR4S1PR2S1PR1 | |
| SCHEMBL14406909 | 0.74 | S1PR3 (0.46) | S1PR3S1PR4S1PR2S1PR1 | |
| Hydrochloric Acid SCHEMBL14333157 | 0.73 | S1PR3 (0.45) | S1PR3S1PR4S1PR2S1PR1 | |
| SCHEMBL12715529 | 0.73 | AHR (0.50) | — | |
| SCHEMBL27906475 | 0.70 | IDO1 (0.34) | S1PR3S1PR4 | |
| SCHEMBL17664159 | 0.69 | S1PR3 (1.00) | S1PR3S1PR4S1PR2S1PR1 | |
| SCHEMBL14033593 | 0.67 | S1PR3 (0.43) | S1PR3S1PR4S1PR2S1PR1 | |
| SCHEMBL14033306 | 0.67 | S1PR3 (0.43) | S1PR3S1PR4S1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |