Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31545550 | 0.77 | SIGMAR1 (0.66) | SLC6A2SLC6A3SLC6A4FPR2ACACB | |
| Hydrochloric Acid SCHEMBL4681889 | 0.72 | SIGMAR1 (0.66) | SLC6A2SLC6A3SLC6A4ACACBSIGMAR1 | |
| SCHEMBL7316113 | 0.72 | TAAR1 (0.63) | SLC6A2SLC6A3SLC6A4ACACBCYP2D6 | |
| SCHEMBL21286088 | 0.72 | TAAR1 (0.63) | SLC6A2SLC6A3SLC6A4ACACBCYP2D6 | |
| SCHEMBL178533 | 0.72 | TAAR1 (0.63) | SLC6A2SLC6A3SLC6A4ACACBCYP2D6 | |
| SCHEMBL8091283 | 0.71 | SIGMAR1 (0.79) | CYP1A2CYP3A4CYP2D6TSHRSIGMAR1 | |
| SCHEMBL11162290 | 0.71 | SLC6A2 (0.55) | SLC6A2SLC6A3SLC6A4FPR2ACACB | |
| Hydrochloric Acid SCHEMBL23524375 | 0.71 | TAAR1 (0.61) | SLC6A2SLC6A3SLC6A4ACACBCYP2D6 | |
| SCHEMBL13996924 | 0.71 | CYP1A2 (0.66) | SLC6A2SLC6A3SLC6A4FPR2ACACB | |
| SCHEMBL17865626 | 0.71 | SLC6A4 (0.77) | SLC6A4CYP1A2CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |