Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HRH1 | P35367 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715025 | 0.78 | HTR2A (0.46) | TAAR1HTR2AHRH1LMNATDP1 | |
| SCHEMBL2923052 | 0.77 | CYP2C19 (0.52) | TSHRTAAR1HTR2AHRH1CYP2C19 | |
| SCHEMBL6929616 | 0.77 | TSHR (0.44) | TSHRTAAR1HTR2AHRH1LMNA | |
| Ammonia Solution, Strong SCHEMBL28836131 | 0.76 | CYP2C19 (0.50) | TSHRTAAR1HTR2AHRH1CYP2C19 | |
| SCHEMBL10510095 | 0.74 | CYP2C19 (0.39) | TAAR1HTR2AHRH1LMNATDP1 | |
| SCHEMBL2372932 | 0.74 | TAAR1 (0.54) | TAAR1HTR2AHRH1LMNATRPA1 | |
| SCHEMBL212179 | 0.73 | LMNA (0.52) | TSHRTAAR1HTR2AHRH1LMNA | |
| SCHEMBL13594208 | 0.73 | LMNA (0.52) | TSHRTAAR1HTR2AHRH1LMNA | |
| SCHEMBL2372727 | 0.73 | TAAR1 (0.37) | TSHRTAAR1HTR2AHRH1LMNA | |
| SCHEMBL266309 | 0.73 | SCN4A (0.45) | TAAR1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547665-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011113756-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-22 | — | — | WO | disclosed |