SCHEMBL23716892

SCHEMBL23716892

COc1ccc(COC(=O)[C@@H]2CCCN2)c(OC)c1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.48
MEN1 O00255 4/20 0.48
ALDH1A1 P00352 2/20 0.47
POLB P06746 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 3/20 0.46
MAPK1 P28482 1/20 0.46
KDM4E B2RXH2 1/20 0.43
GHSR Q92847 1/20 0.41
CA2 P00918 1/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
ALOX15 P16050 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
HTR2B P41595 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30261137 0.80 ALDH1A1 (0.59) KMT2AMEN1ALDH1A1POLBTDP1
SCHEMBL1766751 0.77 KMT2A (0.51) KMT2AMEN1ALDH1A1POLBTDP1
SCHEMBL12533279 0.77 KMT2A (0.51) KMT2AMEN1ALDH1A1POLBTDP1
SCHEMBL23961047 0.77 KMT2A (0.51) KMT2AMEN1ALDH1A1POLBTDP1
SCHEMBL23959329 0.77 KMT2A (0.54) KMT2AMEN1ALDH1A1POLBTDP1
SCHEMBL1766747 0.77 KMT2A (0.51) KMT2AMEN1ALDH1A1POLBTDP1
SCHEMBL23961091 0.77 KMT2A (0.54) KMT2AMEN1ALDH1A1POLBTDP1
SCHEMBL25566925 0.75 TSHR (0.53) KMT2AMEN1ALDH1A1POLBTDP1
SCHEMBL23961118 0.75 TSHR (0.53) KMT2AMEN1ALDH1A1POLBTDP1
SCHEMBL14920847 0.74 FKBP1A (0.52) KMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3862431-B1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES TORAY INDUSTRIES (JP) 2024-06-26 EP disclosed
EP-3862431-B1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES TORAY INDUSTRIES (JP) 2024-06-26 EP disclosed
US-20240110186-A1 METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES TORAY INDUSTRIES, INC. (JP) 2024-04-04 US disclosed
US-11891602-B2 Method of producing hairpin single-stranded RNA molecules TORAY INDUSTRIES, INC. (JP) 2024-02-06 US disclosed
US-20210317495-A1 METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES TORAY INDUSTRIES, INC. (JP) 2021-10-14 US disclosed
US-20210317495-A1 METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES TORAY INDUSTRIES, INC. (JP) 2021-10-14 US disclosed
EP-3862431-A1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES Toray Industries, Inc. (JP) 2021-08-11 EP disclosed
EP-3862431-A1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES Toray Industries, Inc. (JP) 2021-08-11 EP disclosed