Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ELOVL1 | Q9BW60 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384190 | 0.78 | ALDH1A1 (0.47) | MAPTL3MBTL1GAALMNAKDM4E | |
| SCHEMBL6075526 | 0.78 | KMT2A (0.53) | MAPTL3MBTL1ELOVL1LMNAKDM4E | |
| SCHEMBL15352886 | 0.78 | KMT2A (0.40) | CYP2C9MAPTHTTTSHRKDM4E | |
| SCHEMBL7092735 | 0.78 | ALDH1A1 (0.49) | MAPTHTTGAALMNAKDM4E | |
| SCHEMBL28835069 | 0.78 | CYP2A6 (0.53) | HTTGAA | |
| SCHEMBL30354367 | 0.77 | ALDH1A1 (0.46) | MAPTL3MBTL1GAALMNAKDM4E | |
| SCHEMBL29000076 | 0.77 | ALDH1A1 (0.46) | MAPTL3MBTL1GAALMNAKDM4E | |
| SCHEMBL13736329 | 0.77 | MAPT (0.48) | CYP2C9MAPTTSHRKDM4ENPC1 | |
| SCHEMBL15352613 | 0.77 | MEN1 (0.57) | L3MBTL1ALDH1A1 | |
| SCHEMBL15352749 | 0.77 | SMN1; SMN2 (0.41) | MAPTHTTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681755-A | SOLUTION COMPRISING METAL IONS, MOLAR EXCESS OF HISTIDINE OR IMIDAZOLE COMPLEXING AGENT, REDUCING AGENT; QUALITATIVE OR QUANTITATIVE DETERMINATION OF COMPONENTS OF AGGREGATE | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-10-28 | — | — | US | claimed |
| US-5674755-A | Method for depositing metal particles on a marker | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-10-07 | — | — | US | claimed |
| EP-0446993-B1 | Light stable physical developer | JANSSEN PHARMACEUTICA NV (BE) | 1997-06-04 | — | — | EP | claimed |
| US-5206122-A | Aqueous solution of silver ions, desensitizer, reducing agent; immunological detection of antigens | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-04-27 | — | — | US | claimed |
| EP-0293947-B1 | METHOD FOR DEPOSITING METAL PARTICLES ON A MARKER | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-11-25 | — | — | EP | claimed |
| EP-0446993-A1 | Light stable physical developer | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-09-18 | — | — | EP | claimed |
| EP-0293947-A1 | Method for depositing metal particles on a marker | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-12-07 | — | — | EP | claimed |
| CN-116003322-B | Pyrazole ether compound as well as preparation method and application thereof | 南通泰禾化工股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-116003322-A | Pyrazole ether compound as well as preparation method and application thereof | 南通泰禾化工股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2023284761-A1 | PYRAZOLE ETHER COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 南通泰禾化工股份有限公司 | 2023-01-19 | — | — | WO | disclosed |
| WO-2023284761-A1 | PYRAZOLE ETHER COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 南通泰禾化工股份有限公司 | 2023-01-19 | — | — | WO | disclosed |
| CN-108503587-B | Amide compound and application thereof | 上海晓明检测技术服务有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-109096194-B | Biguanide derivative, pharmaceutical composition, preparation method and application | 湖南师范大学 | 2022-02-08 | — | — | CN | disclosed |
| EP-0401913-B1 | A solid phase assay for use with a physical developer | JANSSEN PHARMACEUTICA NV (BE) | 1995-01-25 | — | — | EP | disclosed |
| US-5206122-A | Aqueous solution of silver ions, desensitizer, reducing agent; immunological detection of antigens | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-04-27 | — | — | US | disclosed |
| EP-0293947-B1 | METHOD FOR DEPOSITING METAL PARTICLES ON A MARKER | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-11-25 | — | — | EP | disclosed |
| EP-0446993-A1 | Light stable physical developer | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-09-18 | — | — | EP | disclosed |
| EP-0401913-A1 | A solid phase assay for use with a physical developer | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-12-12 | — | — | EP | disclosed |
| EP-0293947-A1 | Method for depositing metal particles on a marker | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-12-07 | — | — | EP | disclosed |
| US-4531005-A | Pyrazol-4-yl phosphites | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-07-23 | — | — | US | disclosed |