Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19011865 | 1.00 | CYP4F2 (0.34) | CYP4F2CYP4A11MEN1NPC1RAB9A | |
| SCHEMBL1951057 | 0.89 | MMP2 (0.39) | CYP4F2CYP4A11MEN1NPC1RAB9A | |
| SCHEMBL31297015 | 0.88 | MMP2 (0.41) | CYP4F2CYP4A11MEN1NPC1RAB9A | |
| SCHEMBL10206359 | 0.81 | ALDH1A1 (0.33) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL10206358 | 0.80 | MEN1 (0.32) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL10205621 | 0.80 | MEN1 (0.33) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25897225 | 0.79 | MMP2 (0.39) | CYP4F2CYP4A11MEN1NPC1RAB9A | |
| SCHEMBL18365736 | 0.78 | NPC1 (0.32) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL27330337 | 0.77 | USP2 (0.38) | CYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL2635493 | 0.77 | MMP2 (0.40) | CYP4F2CYP4A11MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858349-A1 | NITROGEN-CONTAINING SPIRO-RING COMPOUND AND MEDICINAL USE OF SAME | Japan Tobacco Inc. (JP) | 2021-08-04 | — | — | EP | disclosed |