Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187609 | 0.84 | MAPT (0.41) | ALDH1A1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL20187610 | 0.84 | MAPT (0.41) | ALDH1A1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL10987634 | 0.76 | MEN1 (0.58) | ALDH1A1SMN1; SMN2GAAMAPTMAPK1 | |
| SCHEMBL91576 | 0.71 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2POLBGAAMAPT | |
| Acetic Acid SCHEMBL8059245 | 0.71 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2NPC1TP53POLB | |
| SCHEMBL10134063 | 0.70 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2NPC1TP53POLB | |
| SCHEMBL2612387 | 0.67 | SMN1; SMN2 (0.73) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL10988374 | 0.65 | MEN1 (0.54) | ALDH1A1SMN1; SMN2GAAMAPTMAPK1 | |
| SCHEMBL10989405 | 0.65 | MEN1 (0.54) | ALDH1A1SMN1; SMN2GAAMAPTMAPK1 | |
| SCHEMBL92485 | 0.65 | GAA (0.55) | ALDH1A1SMN1; SMN2NPC1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544979-B1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-08-04 | — | — | EP | disclosed |