Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676084 | 0.87 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2TP53POLBMAPT | |
| SCHEMBL5213000 | 0.83 | GABRA5 (0.53) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL6878797 | 0.83 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2RAB9ANPC1TP53 | |
| Hydrochloric Acid SCHEMBL6152648 | 0.81 | GABRA5 (0.51) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL6152646 | 0.81 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL11143253 | 0.81 | KMT2A (0.40) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL11143259 | 0.81 | CSNK2A1 (0.46) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL4968797 | 0.80 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL5979871 | 0.78 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2TP53POLBMAPT | |
| SCHEMBL21044199 | 0.78 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
| US-7781461-B2 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2010-08-24 | — | — | US | disclosed |
| US-7265130-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| US-4560765-A | USING 183-THIAZOL-4-YL GLYOXYLIC ACID AS INTERMEDIATE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-24 | — | — | US | disclosed |
| US-4440766-A | CEPHALOSPORINS; BACTERICIDES; MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| US-4303655-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | ALDH1A1 4599/4885SMN1; SMN2 2197/4885RAB9A 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.