Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | ME2 | P23368 | 1/20 | 0.49 |
| ▸ | ME1 | P48163 | 1/20 | 0.49 |
| ▸ | ME3 | Q16798 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23719046 | 0.92 | GFER (0.58) | NPC1TDP1FKBP1APOLBL3MBTL1 | |
| SCHEMBL23719112 | 0.90 | ALDH1A1 (0.57) | NPC1TDP1FKBP1AL3MBTL1TSHR | |
| SCHEMBL23719106 | 0.86 | NPC1 (0.54) | NPC1TDP1FKBP1APOLBL3MBTL1 | |
| SCHEMBL7381627 | 0.81 | NPC1 (0.65) | NPC1TDP1FKBP1APOLBL3MBTL1 | |
| SCHEMBL23718995 | 0.80 | NPC1 (0.60) | NPC1TDP1FKBP1APOLBL3MBTL1 | |
| SCHEMBL2700497 | 0.80 | NPC1 (0.63) | NPC1TDP1FKBP1APOLBL3MBTL1 | |
| SCHEMBL23719071 | 0.79 | DRD2 (0.44) | KMT2AGFERMEN1MAPTEPHX2 | |
| SCHEMBL7131839 | 0.78 | NPC1 (0.86) | NPC1TDP1FKBP1APOLBL3MBTL1 | |
| SCHEMBL13593925 | 0.77 | NPC1 (0.60) | NPC1TDP1FKBP1APOLBL3MBTL1 | |
| SCHEMBL12195386 | 0.77 | NPC1 (0.56) | NPC1TDP1FKBP1APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |