Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809772 | 0.89 | KDM1A (0.74) | NPC1RAB9AGAAKMT2ASMN1; SMN2 | |
| SCHEMBL5809768 | 0.89 | KDM1A (0.74) | NPC1RAB9AGAAKMT2ASMN1; SMN2 | |
| SCHEMBL23719304 | 0.88 | RAB9A (0.80) | NPC1RAB9ACTDSP1GAAKMT2A | |
| SCHEMBL27178021 | 0.86 | ATM (0.74) | NPC1RAB9AGAAKMT2ASMN1; SMN2 | |
| SCHEMBL27178027 | 0.86 | ATM (0.74) | NPC1RAB9AGAAKMT2ASMN1; SMN2 | |
| SCHEMBL27178266 | 0.84 | CYP3A4 (0.80) | NPC1RAB9AGAAKMT2ASMN1; SMN2 | |
| SCHEMBL10805645 | 0.84 | NPC1 (0.67) | NPC1RAB9AGAAKMT2ASMN1; SMN2 | |
| SCHEMBL27178271 | 0.84 | CYP3A4 (0.80) | NPC1RAB9AGAAKMT2ASMN1; SMN2 | |
| SCHEMBL27177982 | 0.84 | NPC1 (0.67) | NPC1RAB9AGAAKMT2ASMN1; SMN2 | |
| SCHEMBL1638785 | 0.84 | RAB9A (0.70) | NPC1RAB9ACTDSP1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238140-A1 | Compounds for Targeting Cancer Stem Cells | THE GENERAL HOSPITAL CORPORATION | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238140-A1 | Compounds for Targeting Cancer Stem Cells | G3BP1, G3BP2, HMGB2 | NPC1 1728/4885RAB9A 2930/4885CTDSP1 1663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.