Sugi Predict

Sugi Predict / Compounds / SCHEMBL23719569

SCHEMBL23719569

SCHEMBL23719569

C1=Cc2c(c(-c3ccccc3)c3ccccc3c2-c2ccc3c(c2)sc2c(-c4c5ccccc5c(-c5cccc6c5sc5ccccc56)c5ccccc45)cccc23)CC1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.40
▸ PRKDC P78527 5/20 0.34
▸ PARP14 Q460N5 1/20 0.31
▸ TNKS O95271 1/20 0.31
▸ TNKS2 Q9H2K2 1/20 0.31
▸ F9 P00740 1/20 0.31
▸ PIK3CD O00329 1/20 0.30
▸ BRD4 O60885 1/20 0.30
▸ PIK3CA P42336 1/20 0.30
▸ PIK3CB P42338 1/20 0.30
▸ MTOR P42345 1/20 0.30
▸ PIK3CG P48736 1/20 0.30
▸ KCNH2 Q12809 1/20 0.30
▸ BRDT Q58F21 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23719873 0.93 ALOX5 (0.33) ALOX5PRKDC
SCHEMBL23472844 0.92 ALOX5 (0.38) ALOX5PRKDCPARP14
SCHEMBL20650863 0.91 ALOX5 (0.41) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL23472872 0.90 ALOX5 (0.33) ALOX5PRKDC
SCHEMBL22293492 0.90 ALOX5 (0.34) ALOX5PRKDC
SCHEMBL23720006 0.89 ALOX5 (0.31) ALOX5
SCHEMBL21687015 0.88 ALDH1A1 (0.35) ALOX5
SCHEMBL23719642 0.85 ALOX5 (0.32) ALOX5F9
SCHEMBL23719870 0.85 ALOX5 (0.34) ALOX5
SCHEMBL23719891 0.85 ALOX5 (0.32) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3859812-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2021-08-04 — — EP disclosed
Send feedback