SCHEMBL2371986

SCHEMBL2371986

CC(O)Nc1cccc(O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
KMT2A Q03164 4/20 0.51
CYP3A4 P08684 3/20 0.51
CYP1A2 P05177 2/20 0.51
HSD17B10 Q99714 2/20 0.51
MEN1 O00255 2/20 0.51
USP2 O75604 1/20 0.51
APP P05067 1/20 0.51
HSP90AA1 P07900 1/20 0.51
HSP90AB1 P08238 1/20 0.51
CYP2D6 P10635 1/20 0.51
MAPT P10636 1/20 0.51
CYP2C9 P11712 1/20 0.51
ALOX15 P16050 1/20 0.51
ALOX12 P18054 1/20 0.51
MAPK1 P28482 1/20 0.51
CYP2C19 P33261 1/20 0.51
SNCA P37840 1/20 0.51
TSHR P16473 2/20 0.50
RAPGEF4 Q8WZA2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10915411 0.86 ALDH1A1 (0.50) ALDH1A1KMT2ACYP3A4CYP1A2HSD17B10
SCHEMBL487040 0.85 ALDH1A1 (0.57) ALDH1A1KMT2ACYP3A4CYP1A2HSD17B10
SCHEMBL1004460 0.79 MAPT (0.50) ALDH1A1KMT2ACYP3A4CYP1A2HSD17B10
SCHEMBL5159169 0.79 ALDH1A1 (0.46) ALDH1A1KMT2ACYP3A4CYP1A2HSD17B10
SCHEMBL8085472 0.79 ALDH1A1 (0.55) ALDH1A1KMT2ACYP3A4CYP1A2HSD17B10
SCHEMBL7249243 0.78 ALDH1A1 (0.52) ALDH1A1KMT2ACYP3A4MEN1MAPT
SCHEMBL12826807 0.78 CA12 (0.56) ALDH1A1KMT2ACYP1A2MEN1CYP2D6
SCHEMBL2517913 0.78 SIGMAR1 (0.41) KMT2ACYP3A4MEN1CYP2D6LMNA
SCHEMBL6225932 0.78 ALDH1A1 (0.52) ALDH1A1KMT2ACYP3A4MEN1MAPT
SCHEMBL10998223 0.78 HPGD (0.51) ALDH1A1KMT2AMEN1MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1557157-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2007-03-07 EP claimed
EP-1428503-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2006-05-10 EP claimed
EP-1428502-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2005-10-19 EP claimed
EP-1378228-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2005-10-12 EP claimed
US-20040139561-A1 Composition of the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2004-07-22 US claimed
EP-2547315-A1 COLOURING COMPOSITION FOR KERATIN FIBRES Kao Germany GmbH (DE) 2013-01-23 EP disclosed
WO-2011113452-A1 COLOURING COMPOSITION FOR KERATIN FIBRES KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2011-09-22 WO disclosed
US-20040139561-A1 Composition of the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2004-07-22 US disclosed
EP-0212345-B1 AQUEOUS DYE PREPARATION, ITS MANUFACTURE AND ITS USE CASSELLA Aktiengesellschaft (DE) 1991-09-04 EP disclosed
EP-0212345-A2 Aqueous dye preparation, its manufacture and its use CASSELLA Aktiengesellschaft (DE) 1987-03-04 EP disclosed