Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | UGCG | Q16739 | 2/20 | 0.46 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21405274 | 1.00 | TSHR (0.52) | TSHRL3MBTL1TDP1NAAAGBA1 | |
| SCHEMBL17162054 | 1.00 | TSHR (0.52) | TSHRL3MBTL1TDP1NAAAGBA1 | |
| SCHEMBL31110247 | 0.98 | L3MBTL1 (0.51) | TSHRL3MBTL1TDP1NAAAGBA1 | |
| SCHEMBL24674901 | 0.98 | L3MBTL1 (0.51) | TSHRL3MBTL1TDP1NAAAGBA1 | |
| SCHEMBL13909724 | 0.98 | TSHR (0.54) | TSHRL3MBTL1TDP1NAAAGBA1 | |
| SCHEMBL16346320 | 0.96 | TSHR (0.52) | TSHRL3MBTL1TDP1NAAAGBA1 | |
| SCHEMBL2568514 | 0.96 | L3MBTL1 (0.53) | TSHRL3MBTL1TDP1NAAAGBA1 | |
| SCHEMBL17162099 | 0.96 | TSHR (0.52) | TSHRL3MBTL1TDP1NAAAGBA1 | |
| SCHEMBL20120627 | 0.96 | L3MBTL1 (0.53) | TSHRL3MBTL1TDP1NAAAGBA1 | |
| SCHEMBL30380314 | 0.96 | TSHR (0.52) | TSHRL3MBTL1TDP1NAAAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155006-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES AND USES THEREOF | LES LABORATOIRES SERVIER SAS (FR) | 2021-08-05 | — | — | WO | disclosed |