Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.30 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134993 | 0.95 | TAS1R3 (0.32) | ALDH1A1TAS1R3TAS1R1TAS1R2ALDH1A2 | |
| SCHEMBL13983453 | 0.87 | — | — | |
| SCHEMBL23764901 | 0.87 | KDM4E (0.31) | ALDH1A1KDM4EHPGDTAS1R3TAS1R1 | |
| SCHEMBL172098 | 0.87 | SLC6A2 (0.31) | ALDH1A1KDM4EHPGD | |
| SCHEMBL22561839 | 0.82 | — | — | |
| SCHEMBL26375129 | 0.82 | TAS1R3 (0.38) | KDM4EHPGDTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL28781614 | 0.79 | — | — | |
| SCHEMBL12247574 | 0.79 | — | — | |
| SCHEMBL9506583 | 0.79 | — | — | |
| SCHEMBL5176523 | 0.78 | TAAR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022036297-A1 | NON-HYDRATED KETONE INHIBITORS OF NAV1.7 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2021186023-A1 | AN ORGANIC ELECTRONIC DEVICE COMPRISING A SUBSTRATE, AN ANODE LAYER, A CATHODE LAYER, AT LEAST ONE FIRST EMISSION LAYER, AND A HOLE INJECTION LAYER THAT COMPRISES A METAL COMPLEX | NOVALED GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021151959-A1 | AN ORGANIC ELECTRONIC DEVICE COMPRISING AN ANODE LAYER, A CATHODE LAYER, AT LEAST ONE EMISSION LAYER (EML) AND AT LEAST ONE HOLE INJECTION LAYER (HIL) | NOVALED GMBH (DE) | 2021-08-05 | — | — | WO | disclosed |