SCHEMBL172098

SCHEMBL172098

CCCc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
DAO P14920 1/20 0.30
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9506583 0.91
SCHEMBL16575391 0.90 KDM4E (0.32) KDM4EALDH1A1GAAHPGDTYMP
SCHEMBL24063626 0.87
SCHEMBL23720718 0.87 ALDH1A1 (0.30) KDM4EALDH1A1HPGD
SCHEMBL18134993 0.85 TAS1R3 (0.32) ALDH1A1
SCHEMBL24063604 0.83
SCHEMBL24248341 0.83 KDM4E (0.31) KDM4EALDH1A1GAAHPGD
SCHEMBL9785428 0.83
SCHEMBL20226509 0.83 NOS2 (0.33)
SCHEMBL8166647 0.83 ESR1 (0.38) KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022083758-A1 ANTICOAGULANT ARTIFICIAL HEART VALVE MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 吉林启明皓月生物科技有限公司 2022-04-28 WO claimed
CN-119708503-A Preparation method of liquid hyperbranched polycarbosilane containing epoxy active groups and application of liquid hyperbranched polycarbosilane in photocuring 3D printing 上海信斯帝克新材料有限公司 2025-03-28 CN disclosed
CN-119708503-A Preparation method of liquid hyperbranched polycarbosilane containing epoxy active groups and application of liquid hyperbranched polycarbosilane in photocuring 3D printing 上海信斯帝克新材料有限公司 2025-03-28 CN disclosed
US-20240025901-A1 METHOD FOR PRODUCING CYCLIC IMIDE COMPOUND, COMPOSITION, AND COMPOUND FUJIFILM CORPORATION (JP) 2024-01-25 US disclosed
US-11785845-B2 Composition FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
EP-3183250-B1 PROCESS FOR PREPARING CRYSTALLINE ORGANIC SEMICONDUCTOR MATERIAL CLAP CO LTD (KR) 2023-10-04 EP disclosed
US-11547354-B2 Bio-electrode composition, bio-electrode, and method for manufacturing a bio-electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-10 US disclosed
EP-4101835-A1 18F-SUBSTITUTED ESTERS OF CYCLOPROPANATED UNSATURATED FATTY ACIDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Blanchette Rockefeller Neurosciences Institute (US) 2022-12-14 EP disclosed
US-20220213104-A1 METHOD FOR PRODUCING CYCLIC IMIDE COMPOUND, COMPOSITION, AND COMPOUND FUJIFILM CORPORATION (JP) 2022-07-07 US disclosed
US-20220213296-A1 DISPERSION LIQUID, COMPOSITION, CURED FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-07-07 US disclosed
US-20080285133-A1 Antireflection Film, Production Method Thereof, Polarizing Plate Using the Antireflection Film and Image Display Device Using the Antireflection Film or Polarizing Plate FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080088925-A1 Antireflection Film, Polarizing Plate And Image Display Utilizing The Same FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-20080038472-A1 Production method of laminate, laminate, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2008-02-14 US disclosed
US-20070287670-A1 HUMAN GLUCAGON-LIKE PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-12-13 US disclosed
US-7244847-B2 Benzimidazole compounds ISIS PHARMACEUTICALS, INC. (US) 2007-07-17 US disclosed
US-20070021331-A1 Methods of using macrocyclic modulators of the ghrelin receptor TRANZYME PHARMA INC. 2007-01-25 US disclosed
EP-0495823-B1 EPOXIDATION OF FLUORINE CONTAINING OLEFINS DU PONT (US) 1994-04-13 EP disclosed
EP-0495823-A1 EPOXIDATION OF FLUORINE CONTAINING OLEFINS. DU PONT (US) 1992-07-29 EP disclosed
US-5084583-A Epoxidation of fluorine containing olefins E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-28 US disclosed
WO-1991005778-A1 EPOXIDATION OF FLUORINE CONTAINING OLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070287670-A1 HUMAN GLUCAGON-LIKE PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS GLP1R, IAPP, GIPR SLC6A2 4493/4885SLC6A4 4570/4885SLC6A3 4604/4885
US-20240025901-A1 METHOD FOR PRODUCING CYCLIC IMIDE COMPOUND, COMPOSITION, AND COMPOUND INF2, NISCH, ITPA SLC6A2 4533/4885SLC6A4 4731/4885SLC6A3 4574/4885
US-11785845-B2 Composition ADH1A, ADH1C, SLC19A2 SLC6A2 202/4885SLC6A4 469/4885SLC6A3 733/4885
US-11547354-B2 Bio-electrode composition, bio-electrode, and method for manufacturing a bio-electrode KCNN1, KCNN2, KCNN3 SLC6A2 1727/4885SLC6A4 2765/4885SLC6A3 1469/4885
US-20070021331-A1 Methods of using macrocyclic modulators of the ghrelin receptor GHSR, GHRHR, GIPR SLC6A2 3588/4885SLC6A4 2336/4885SLC6A3 2277/4885
US-20220213104-A1 METHOD FOR PRODUCING CYCLIC IMIDE COMPOUND, COMPOSITION, AND COMPOUND INF2, NISCH, ITPA SLC6A2 4533/4885SLC6A4 4731/4885SLC6A3 4574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.