Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16133500 | 0.83 | TSHR (0.43) | TSHRTRPA1ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL6058134 | 0.83 | TSHR (0.43) | TSHRTRPA1ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL2477593 | 0.81 | TSHR (0.50) | TSHRTRPA1ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL9489967 | 0.77 | TSHR (0.46) | TSHRTRPA1ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL1052816 | 0.77 | TSHR (0.46) | TSHRTRPA1ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL544445 | 0.77 | TSHR (0.46) | TSHRTRPA1ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL28211563 | 0.74 | TSHR (0.43) | TSHRTRPA1ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL28557277 | 0.72 | TSHR (0.47) | TSHRTRPA1ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL7035520 | 0.72 | TRPA1 (0.42) | TSHRTRPA1ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL28671673 | 0.71 | TRPA1 (0.41) | TSHRTRPA1ALDH1A1USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113756-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-22 | — | — | WO | disclosed |