SCHEMBL2477593

SCHEMBL2477593

N#CC(C=CC(C#N)c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
TRPA1 O75762 1/20 0.50
CYP2D6 P10635 1/20 0.37
CYP1A2 P05177 1/20 0.36
DPP4 P27487 2/20 0.36
F2 P00734 1/20 0.36
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
ALDH1A1 P00352 3/20 0.34
HTT P42858 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C1 Q04828 1/20 0.34
MAP2K1 Q02750 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16133500 0.87 TSHR (0.43) TSHRTRPA1CYP1A2DPP4F2
SCHEMBL6058134 0.87 TSHR (0.43) TSHRTRPA1CYP1A2DPP4F2
SCHEMBL28671673 0.83 TRPA1 (0.41) TSHRTRPA1CYP2D6CYP1A2ALDH1A1
SCHEMBL1052816 0.81 TSHR (0.46) TSHRTRPA1DPP4F2ESR1
SCHEMBL9489967 0.81 TSHR (0.46) TSHRTRPA1CYP2D6CYP1A2DPP4
SCHEMBL544445 0.81 TSHR (0.46) TSHRTRPA1CYP2D6CYP1A2DPP4
SCHEMBL2372210 0.81 TSHR (0.46) TSHRTRPA1DPP4F2ALDH1A1
SCHEMBL28211563 0.78 TSHR (0.43) TSHRTRPA1CYP2D6CYP1A2DPP4
SCHEMBL7035520 0.76 TRPA1 (0.42) TSHRTRPA1CYP2D6CYP1A2ALDH1A1
SCHEMBL28557277 0.76 TSHR (0.47) TSHRTRPA1CYP2D6CYP1A2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10003103-B2 Additive having cyano group for non-aqueous electrolyte and electrochemical device using the same LG CHEM, LTD. (KR) 2018-06-19 US claimed
US-10003103-B2 Additive having cyano group for non-aqueous electrolyte and electrochemical device using the same LG CHEM, LTD. (KR) 2018-06-19 US disclosed
US-9287583-B2 Additive having cyano group for non-aqueous electrolyte and electrochemical device using the same LG CHEM, LTD. (KR) 2016-03-15 US disclosed
US-20150333372-A1 ADDITIVE HAVING CYANO GROUP FOR NON-AQUEOUS ELECTROLYTE AND ELECTROCHEMICAL DEVICE USING THE SAME LG CHEM, LTD. (KR) 2015-11-19 US disclosed
CN-101512822-B Cyano group-containing additive for non-aqueous electrolyte and electrochemical device using the same LG CHEM, LTD. (KR) 2011-12-28 CN disclosed
EP-2044645-B1 ADDITIVE HAVING CYANO GROUP FOR NON-AQUEOUS ELECTROLYTE AND ELECTROCHEMICAL DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2011-10-12 EP disclosed
CN-101512822-A Cyano group-containing additive for non-aqueous electrolyte and electrochemical device using the same LG CHEMICAL LTD (KR) 2009-08-19 CN disclosed
US-20080020287-A1 ADDITIVE HAVING CYANO GROUP FOR NON-AQUEOUS ELECTROLYTE AND ELECTROCHEMICAL DEVICE USING THE SAME LG CHEM, LTD. (KR) 2008-01-24 US disclosed