Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12405037 | 0.81 | MGAM (0.63) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL9220609 | 0.79 | MGAM (0.61) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL12101112 | 0.79 | MGAM (0.39) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL950437 | 0.78 | MGAM (0.60) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL28278979 | 0.78 | MGAM (0.60) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL29527233 | 0.77 | MGAM (0.58) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL3365551 | 0.77 | MGAM (0.58) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL22777233 | 0.77 | MGAM (0.58) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL3365613 | 0.77 | MGAM (0.58) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL5623383 | 0.77 | ALDH1A1 (0.59) | MGAMKDM4EALOX15TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151265-A1 | PHARMACEUTICAL USE OF ALDEHYDE-BASED COMPOUND | 中国科学院上海药物研究所 | 2021-08-05 | — | — | WO | disclosed |