SCHEMBL23723017

SCHEMBL23723017

O=C(O)CC1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 9/20 0.47
KMT2A Q03164 2/20 0.43
FABP7 O15540 2/20 0.43
FABP5 Q01469 2/20 0.43
PPARG P37231 1/20 0.42
CHRNB2 P17787 1/20 0.41
CHRNA5 P30532 1/20 0.41
CHRNA7 P36544 1/20 0.41
CHRNA4 P43681 1/20 0.41
F2 P00734 1/20 0.41
CHRM3 P20309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29989803 1.00 FFAR1 (0.47) FFAR1KMT2AFABP7FABP5PPARG
SCHEMBL20590863 1.00 FFAR1 (0.47) FFAR1KMT2AFABP7FABP5PPARG
SCHEMBL29401491 1.00 FFAR1 (0.47) FFAR1KMT2AFABP7FABP5PPARG
SCHEMBL29855161 1.00 FFAR1 (0.47) FFAR1KMT2AFABP7FABP5PPARG
SCHEMBL29855051 1.00 FFAR1 (0.47) FFAR1KMT2AFABP7FABP5PPARG
SCHEMBL119493 1.00 FFAR1 (0.47) FFAR1KMT2AFABP7FABP5PPARG
SCHEMBL2564462 0.96 FFAR1 (0.44) FFAR1KMT2AFABP7FABP5PPARG
SCHEMBL29855049 0.96 FFAR1 (0.44) FFAR1KMT2AFABP7FABP5PPARG
SCHEMBL25177921 0.96 FFAR1 (0.44) FFAR1KMT2AFABP7FABP5PPARG
SCHEMBL2565677 0.96 FFAR1 (0.44) FFAR1KMT2AFABP7FABP5PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-12-05 US disclosed
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2024-04-18 US disclosed
EP-4316503-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-07 EP disclosed
US-11667675-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2023-06-06 US disclosed
US-20230151060-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-05-18 US disclosed
US-20210246166-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2021-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 FFAR1 4251/4885KMT2A 4690/4885FABP7 2453/4885
US-20230151060-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION KRAS, NRAS, HRAS FFAR1 3629/4885KMT2A 3145/4885FABP7 4602/4885
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION KRAS, NRAS, HRAS FFAR1 3629/4885KMT2A 3145/4885FABP7 4602/4885
US-11667675-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 FFAR1 4251/4885KMT2A 4690/4885FABP7 2453/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS FFAR1 3629/4885KMT2A 3145/4885FABP7 4602/4885
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SERPINB1, SPINT2 FFAR1 4251/4885KMT2A 4690/4885FABP7 2453/4885
US-20210246166-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SERPINB1, SPINT2 FFAR1 4251/4885KMT2A 4690/4885FABP7 2453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.