Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723341 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HDAC1HDAC2APEX1SMN1; SMN2 | |
| SCHEMBL26758596 | 0.85 | KDM4E (0.34) | ALDH1A1SMN1; SMN2HDAC8POLBPPARG | |
| SCHEMBL30633628 | 0.85 | KDM4E (0.34) | ALDH1A1SMN1; SMN2HDAC8POLBPPARG | |
| SCHEMBL23723347 | 0.83 | ALDH1A1 (0.41) | ALDH1A1APEX1SMN1; SMN2PKMKMT2A | |
| SCHEMBL23723345 | 0.83 | ALDH1A1 (0.41) | ALDH1A1APEX1SMN1; SMN2PKMKMT2A | |
| SCHEMBL23723267 | 0.78 | KMT2A (0.41) | ALDH1A1APEX1SMN1; SMN2KMT2APOLB | |
| SCHEMBL23723269 | 0.78 | KMT2A (0.41) | ALDH1A1APEX1SMN1; SMN2KMT2APOLB | |
| SCHEMBL23723321 | 0.77 | APEX1 (0.38) | ALDH1A1HDAC1HDAC2APEX1SMN1; SMN2 | |
| SCHEMBL23723322 | 0.77 | APEX1 (0.38) | ALDH1A1HDAC1HDAC2APEX1SMN1; SMN2 | |
| SCHEMBL21646305 | 0.69 | GAA (0.40) | ALDH1A1SMN1; SMN2PKMKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230349907-A1 | BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2023-11-02 | — | — | US | disclosed |
| WO-2021155439-A1 | BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2021-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230349907-A1 | BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF | MAOB, LOX, LPO | ALDH1A1 367/4885HDAC1 2419/4885HDAC2 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.