Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL27941234 | 0.90 | CRBN (0.56) | CRBNALDH1A1TSHRLMNANFKB1 | |
| Butane SCHEMBL9394572 | 0.87 | CRBN (0.53) | CRBNTSHRLMNANFKB1BLM | |
| Butane SCHEMBL28303788 | 0.87 | CRBN (0.53) | CRBNTSHRLMNANFKB1BLM | |
| Alcohol SCHEMBL18426864 | 0.83 | CRBN (0.43) | CRBNALDH1A1TSHRLMNANFKB1 | |
| Alcohol SCHEMBL28816200 | 0.83 | CRBN (0.43) | CRBNALDH1A1TSHRLMNANFKB1 | |
| Ethylene Glycol SCHEMBL20953848 | 0.83 | CRBN (0.47) | CRBNALDH1A1TSHRLMNANFKB1 | |
| Butanedione SCHEMBL20184746 | 0.83 | CRBN (0.65) | CRBNALDH1A1TSHRLMNANFKB1 | |
| SCHEMBL15045 | 0.82 | — | — | |
| SCHEMBL27939070 | 0.82 | CRBN (0.60) | CRBNALDH1A1TSHRLMNANFKB1 | |
| SCHEMBL27560286 | 0.82 | CRBN (0.60) | CRBNALDH1A1TSHRLMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230098760-A1 | FORMULATIONS PROVIDING LONG-LASTING FRAGRANCE PERFORMANCE | FIRMENICH SA (CH) | 2023-03-30 | — | — | US | claimed |
| WO-2021156242-A1 | FORMULATIONS PROVIDING LONG-LASTING FRAGRANCE PERFORMANCE | FIRMENICH SA (CH) | 2021-08-12 | — | — | WO | claimed |
| US-20230098760-A1 | FORMULATIONS PROVIDING LONG-LASTING FRAGRANCE PERFORMANCE | FIRMENICH SA (CH) | 2023-03-30 | — | — | US | disclosed |
| CN-115023215-A | Formulations providing long-lasting fragrance performance | 弗门尼舍有限公司 | 2022-09-06 | — | — | CN | disclosed |
| WO-2021156242-A1 | FORMULATIONS PROVIDING LONG-LASTING FRAGRANCE PERFORMANCE | FIRMENICH SA (CH) | 2021-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230098760-A1 | FORMULATIONS PROVIDING LONG-LASTING FRAGRANCE PERFORMANCE | TRPC5, TRPA1, CYP3A5 | CRBN 2988/4885ALDH1A1 593/4885TSHR 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.