⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30187440 | 1.00 | — | — | |
| SCHEMBL937861 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL35211807 | 0.97 | — | — | |
| SCHEMBL8381116 | 0.89 | TP53 (0.62) | — | |
| SCHEMBL19006601 | 0.88 | — | — | |
| SCHEMBL22535894 | 0.88 | — | — | |
| SCHEMBL3647508 | 0.88 | — | — | |
| SCHEMBL9767380 | 0.87 | TP53 (0.60) | — | |
| SCHEMBL5228082 | 0.86 | TP53 (1.00) | — | |
| SCHEMBL4079339 | 0.86 | TP53 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100381-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158481-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA, INC. (US) | 2021-08-12 | — | — | WO | disclosed |