Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.42 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704526 | 0.83 | AHCY (0.47) | AHCYADORA2AADORA2BSLC29A1ADORA3 | |
| SCHEMBL30673317 | 0.81 | ADORA2A (0.41) | AHCYADORA2AADORA2BSLC29A1ADORA3 | |
| SCHEMBL2372511 | 0.81 | ADORA2A (0.41) | AHCYADORA2AADORA2BSLC29A1ADORA3 | |
| SCHEMBL1093482 | 0.80 | ADORA3 (0.49) | AHCYADORA2AADORA2BSLC29A1ADORA3 | |
| SCHEMBL8651423 | 0.80 | PI4KA (0.52) | AHCYADORA2AADORA2BSLC29A1ADORA3 | |
| SCHEMBL1434028 | 0.77 | ADORA3 (0.49) | AHCYADORA2AADORA2BSLC29A1ADORA3 | |
| SCHEMBL622587 | 0.76 | ADORA3 (0.49) | AHCYADORA2AADORA2BSLC29A1ADORA3 | |
| SCHEMBL2373109 | 0.76 | ADORA2A (0.49) | AHCYADORA2AADORA2BSLC29A1ADORA3 | |
| SCHEMBL2372382 | 0.76 | ADORA2A (0.49) | AHCYADORA2AADORA3ADORA1 | |
| SCHEMBL10770761 | 0.75 | ADORA3 (0.46) | ADORA2AADORA2BSLC29A1ADORA3DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552932-A1 | ADENOSINE COMPOUNDS AND THEIR USE THEREOF | Inotek Pharmaceuticals Corporation (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011119919-A1 | ADENOSINE COMPOUNDS AND THEIR USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2011-09-29 | — | — | WO | disclosed |