Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23725924 | 0.81 | RHEB (0.35) | — | |
| SCHEMBL23726042 | 0.74 | — | — | |
| SCHEMBL23725883 | 0.70 | HTR6 (0.43) | — | |
| SCHEMBL23780910 | 0.69 | GRIN2D (0.36) | — | |
| SCHEMBL23725614 | 0.61 | ADORA2A (0.38) | — | |
| SCHEMBL22789992 | 0.60 | RHEB (0.37) | — | |
| SCHEMBL2125118 | 0.60 | LCK (0.40) | ADRB2 | |
| SCHEMBL15572559 | 0.59 | KDM4E (0.43) | — | |
| SCHEMBL23725130 | 0.58 | NPC1 (0.33) | — | |
| SCHEMBL31661068 | 0.57 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100381-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158481-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA, INC. (US) | 2021-08-12 | — | — | WO | disclosed |