Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561734 | 0.85 | OPRM1 (0.49) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23727470 | 0.83 | OPRM1 (0.41) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23727554 | 0.82 | OPRM1 (0.40) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23727000 | 0.82 | OPRM1 (0.40) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23726723 | 0.78 | OPRM1 (0.38) | OPRM1 | |
| SCHEMBL23727874 | 0.73 | CYP1A2 (0.38) | OPRM1 | |
| SCHEMBL12868735 | 0.73 | ALDH1A1 (0.39) | OPRM1SLC6A4 | |
| Hydrochloric Acid SCHEMBL23727074 | 0.72 | CYP1A2 (0.37) | OPRM1 | |
| SCHEMBL21867155 | 0.71 | OPRM1 (0.48) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12503700 | 0.71 | ACACB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100407-A1 | QUINUCLIDINONE ANALOGUES AS ANTICANCER AGENTS | Newave Pharmaceutical Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158948-A1 | QUINUCLIDINONE ANALOGUES AS ANTICANCER AGENTS | NEWAVE PHARMACEUTICAL INC. (US) | 2021-08-12 | — | — | WO | disclosed |