Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 18/20 | 0.35 |
| ▸ | MMP13 | P45452 | 5/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 4/20 | 0.35 |
| ▸ | MMP3 | P08254 | 4/20 | 0.35 |
| ▸ | MMP7 | P09237 | 4/20 | 0.35 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | MMP14 | P50281 | 4/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121201 | 0.80 | DPP7 (0.41) | MMP2ADAMTS5 | |
| SCHEMBL30013197 | 0.80 | DPP7 (0.41) | MMP2ADAMTS5 | |
| SCHEMBL29835226 | 0.80 | DPP7 (0.41) | MMP2ADAMTS5 | |
| SCHEMBL23745307 | 0.80 | DPP7 (0.41) | MMP2ADAMTS5 | |
| SCHEMBL23745305 | 0.80 | DPP7 (0.41) | MMP2ADAMTS5 | |
| SCHEMBL23728005 | 0.80 | DPP7 (0.41) | MMP2ADAMTS5 | |
| SCHEMBL23728089 | 0.78 | ADAMTS5 (0.48) | MMP2MMP8ADAMTS5MMP13ADAMTS4 | |
| SCHEMBL23728102 | 0.77 | ADAMTS5 (0.58) | MMP2ADAMTS5MMP13ADAMTS4MMP1 | |
| SCHEMBL23728017 | 0.76 | ADAMTS5 (0.40) | MMP2ADAMTS5MMP13ADAMTS4MMP1 | |
| SCHEMBL23727859 | 0.76 | ADAMTS5 (0.52) | MMP2ADAMTS5MMP13ADAMTS4MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100005-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |