Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 12/20 | 0.38 |
| ▸ | MMP2 | P08253 | 5/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745307 | 1.00 | DPP7 (0.41) | DPP7FAPADAMTS5MMP2DPP4 | |
| SCHEMBL31121201 | 1.00 | DPP7 (0.41) | DPP7FAPADAMTS5MMP2DPP4 | |
| SCHEMBL30013197 | 1.00 | DPP7 (0.41) | DPP7FAPADAMTS5MMP2DPP4 | |
| SCHEMBL23745305 | 1.00 | DPP7 (0.41) | DPP7FAPADAMTS5MMP2DPP4 | |
| SCHEMBL29835226 | 1.00 | DPP7 (0.41) | DPP7FAPADAMTS5MMP2DPP4 | |
| SCHEMBL23728003 | 0.80 | MMP2 (0.35) | ADAMTS5MMP2 | |
| SCHEMBL29250257 | 0.80 | ADAMTS5 (0.55) | ADAMTS5MMP2 | |
| SCHEMBL29835134 | 0.80 | ADAMTS5 (0.55) | ADAMTS5MMP2 | |
| SCHEMBL23745214 | 0.80 | ADAMTS5 (0.55) | ADAMTS5MMP2 | |
| SCHEMBL23728091 | 0.80 | ADAMTS5 (0.54) | DPP7ADAMTS5MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052596-B | ADAMTS inhibitor, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| EP-4100005-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2022-12-14 | — | — | EP | disclosed |
| CN-115052596-A | ADAMTS inhibitor, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |