Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 8/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 3/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372319 | 0.88 | DHODH (0.54) | DHODHSMN1; SMN2RORBKDM4EGAA | |
| SCHEMBL2372855 | 0.84 | DHODH (0.71) | DHODHTSHRPDE10AKMT2APTGFR | |
| SCHEMBL2372504 | 0.82 | DHODH (0.69) | DHODHTSHRPDE10AALDH1A1SMN1; SMN2 | |
| SCHEMBL8687492 | 0.82 | DHODH (1.00) | DHODHTSHRPDE10AKMT2A | |
| SCHEMBL2373114 | 0.82 | DHODH (0.62) | DHODHTSHRPDE10APTGFR | |
| SCHEMBL2373336 | 0.82 | DHODH (0.62) | DHODHTSHRPDE10APTGFR | |
| SCHEMBL2373344 | 0.81 | DHODH (0.82) | DHODHTSHRPDE10APTGFR | |
| SCHEMBL2416936 | 0.81 | DHODH (0.58) | DHODHKMT2AALDH1A1SMN1; SMN2XDH | |
| SCHEMBL2373037 | 0.81 | DHODH (0.70) | DHODHTSHRPDE10AKMT2ASMN1; SMN2 | |
| SCHEMBL2417777 | 0.80 | DHODH (0.59) | DHODHTSHRPDE10AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |