Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24510763 | 0.82 | RPS6KA3 (0.42) | RPS6KA3TEAD2ADORA3ADORA2AADORA1 | |
| SCHEMBL13879891 | 0.81 | RPS6KA3 (0.45) | RPS6KA3ADORA3ADORA2AADORA1CYP1A2 | |
| SCHEMBL23728711 | 0.80 | STK17B (0.45) | ADORA3ADORA2AADORA1MAPTNPSR1 | |
| SCHEMBL23745118 | 0.80 | RPS6KA3 (0.43) | RPS6KA3ADORA3ADORA2AADORA1CYP1A2 | |
| SCHEMBL13928636 | 0.76 | HDAC1 (0.34) | RPS6KA3ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL23728948 | 0.76 | CA1 (0.39) | ALDH1A1MAPTSMN1; SMN2HRH3HRH4 | |
| Hydrochloric Acid SCHEMBL23728962 | 0.75 | CA1 (0.38) | ALDH1A1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL14072191 | 0.73 | RPS6KA3 (0.47) | RPS6KA3ADORA3ADORA2AADORA1CYP1A2 | |
| SCHEMBL30125576 | 0.73 | HDAC1 (0.46) | RPS6KA3MAPTNPSR1KDM4EPOLB | |
| SCHEMBL1594748 | 0.73 | ADORA3 (0.46) | ADORA3ADORA2AADORA1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384506-A1 | PROCESS FOR POLYAMIDE SYNTHESIS | Design Therapeutics, Inc. (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023244678-A1 | METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES | Design Therapeutics, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023014793-A1 | PROCESS FOR POLYAMIDE SYNTHESIS | Design Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
| EP-4100404-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158707-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2021-08-12 | — | — | WO | disclosed |