SCHEMBL1594748

SCHEMBL1594748

CCOC(=O)c1nc(N)cn1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 3/20 0.46
ADORA2A P29274 3/20 0.46
ADORA1 P30542 3/20 0.46
ALDH1A1 P00352 7/20 0.44
CYP1A2 P05177 3/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAOA P21397 1/20 0.42
BAZ2B Q9UIF8 1/20 0.41
BAZ2A Q9UIF9 1/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HTT P42858 1/20 0.41
RECQL P46063 1/20 0.41
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1852651 0.98 ALDH1A1 (0.45) ADORA3ADORA2AADORA1ALDH1A1CYP1A2
SCHEMBL14072191 0.87 RPS6KA3 (0.47) ADORA3ADORA2AADORA1ALDH1A1CYP1A2
Imidazole SCHEMBL7131590 0.84 ADORA3 (0.36) ADORA3ADORA2AADORA1ALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL7131591 0.84 ADORA2A (0.37) ADORA3ADORA2AADORA1ALDH1A1CYP1A2
SCHEMBL2028204 0.83 CYP1A2 (0.44) ADORA3ADORA2AADORA1ALDH1A1CYP1A2
SCHEMBL5891162 0.81 NPSR1 (0.39) ALDH1A1HPGDKDM4EHSD17B10TSHR
SCHEMBL12582170 0.80 CYP1A2 (0.42) ADORA3ADORA2AADORA1ALDH1A1CYP1A2
SCHEMBL14072221 0.80 RPS6KA3 (0.43) ADORA3ADORA2AADORA1ALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL5891157 0.79 NPSR1 (0.38) ALDH1A1HPGDKDM4EHSD17B10TSHR
SCHEMBL24897834 0.78 ALDH1A1 (0.40) ADORA3ADORA2AADORA1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12454526-B2 Method for producing pyrrole-imidazole (poly)amide KANEKA CORPORATION (JP) 2025-10-28 US disclosed
WO-2025122764-A1 METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES Design Therapeutics, Inc. (US) 2025-06-12 WO disclosed
EP-4539839-A1 METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES Design Therapeutics, Inc. (US) 2025-04-23 EP disclosed
EP-4539842-A1 METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES Design Therapeutics, Inc. (US) 2025-04-23 EP disclosed
WO-2025076219-A1 METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE Design Therapeutics, Inc. (US) 2025-04-10 WO disclosed
WO-2025076181-A1 METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE Design Therapeutics, Inc. (US) 2025-04-10 WO disclosed
CN-119677513-A Methods and compounds for modulating genetic disease 设计治疗公司 2025-03-21 CN disclosed
CN-119584961-A Methods and compounds for modulating huntington's disease 设计治疗公司 2025-03-07 CN disclosed
EP-4504339-A2 METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE Design Therapeutics, Inc. (US) 2025-02-12 EP disclosed
EP-4460302-A2 COMPOUNDS AND METHODS FOR TREATING FRIEDREICH'S ATAXIA Design Therapeutics, Inc. (US) 2024-11-13 EP disclosed
US-20080176859-A1 HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES AICURIS GMBH & CO. KG (DE) 2008-07-24 US disclosed
US-20080176859-A1 HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES AICURIS GMBH & CO. KG (DE) 2008-07-24 US disclosed
US-20080176859-A1 HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES AICURIS GMBH & CO. KG (DE) 2008-07-24 US disclosed
US-7348427-B2 Antipathogenic benzamide compounds GENESOFT PHARMACEUTICALS, INC. (US) 2008-03-25 US disclosed
US-7348427-B2 Antipathogenic benzamide compounds GENESOFT PHARMACEUTICALS, INC. (US) 2008-03-25 US disclosed
US-20080004275-A1 Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds BAYER HEALTHCARE AG (DE) 2008-01-03 US disclosed
US-20070265240-A1 Sequence Selective Pyrrole and Imidazole Polyamide Metallocomplexes UNIVERSITY OF WESTERN SYDNEY (AU) 2007-11-15 US disclosed
US-20070172826-A1 Electrochemically active ligand for sequence-specific detection of double-stranded nucleic acid molecule JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2007-07-26 US disclosed
US-20070172826-A1 Electrochemically active ligand for sequence-specific detection of double-stranded nucleic acid molecule JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2007-07-26 US disclosed
US-6566336-B1 For therapy and prophylaxis of various gene- inducible diseases JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080176859-A1 HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES TPMT, TYMP, PAICS ADORA3 1451/4885ADORA2A 1139/4885ADORA1 2165/4885
US-20070172826-A1 Electrochemically active ligand for sequence-specific detection of double-stranded nucleic acid molecule POLRMT, POLM, POLI ADORA3 1585/4885ADORA2A 1075/4885ADORA1 834/4885
US-20070265240-A1 Sequence Selective Pyrrole and Imidazole Polyamide Metallocomplexes POLRMT, MPI, PPIF ADORA3 2695/4885ADORA2A 4072/4885ADORA1 3660/4885
US-20080004275-A1 Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds IRF3, EIF2AK2, ZC3HAV1 ADORA3 356/4885ADORA2A 590/4885ADORA1 394/4885
US-12454526-B2 Method for producing pyrrole-imidazole (poly)amide DDC, PAM, AADAC ADORA3 2203/4885ADORA2A 3532/4885ADORA1 3116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.